A 3-part illustration depicting a radioactivity measurement device and radioactive-labeled package, a patient receiving radioligand therapy, and a male health care professional disposing of waste in a radioactivelabeled waste bin.

Providing and administering RLT

This section of the Novartis RLT Institute is designed to help health care professionals (HCPs) understand radiation safety procedures for providing and administering radioligand therapies (RLTs) manufactured by Novartis. It is based on guidelines from regulatory agencies, including the Nuclear Regulatory Commission (NRC), the Department of Transportation (DOT), and the United States Pharmacopeia (USP). Topics include safe transport, administration, and postadministration protocols to prepare the patient and room for subsequent use.

Postadministration

Reportable events

An illustration of a US NRC form.

Misadministration of RLTs may require that the appropriate regulatory bodies be notified (ie, NRC and/or state regulators for Agreement States). Reportable events include, but are not limited to1:

  • Dose delivered differs from the prescribed dose by 20% or more
  • Use of the wrong RLT
  • Use of the wrong route of administration
  • Administration to the wrong patient